Salbutamol Sulfate
- Product Name: Salbutamol Sulfate
- Product Code: AIL510SAL
- CAS No: 51022-70-9
- Grade: BP / USP
- Therapeutic Category: Bronchodilator / β2-adrenergic agonist (used in treatment of asthma, COPD; also known for off-label use in weight management and performance enhancement)
- Molecular Formula: C₁₃H₂₁NO₃ · H₂SO₄
- Molar Mass: C₁₃H₂₁NO₃ · H₂SO₄
- COA: Available
- MSDS: Available
- IUPAC Name: 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol sulfate (2:1)
Salbutamol Sulphate is a short-acting β2-adrenergic receptor agonist (SABA). It is widely prescribed as a rescue medication for quick relief of bronchospasm associated with asthma, chronic obstructive pulmonary disease (COPD), and other reversible airway diseases.
It is the sulfate salt form of salbutamol, which enhances stability and solubility for pharmaceutical formulations (inhalers, tablets, syrups, injectables).
It is the sulfate salt form of salbutamol, which enhances stability and solubility for pharmaceutical formulations (inhalers, tablets, syrups, injectables).
Consists of a phenethylamine backbone substituted with hydroxyl and hydroxymethyl groups, along with a tert-butylamino substituent.
Supplied as the sulfate salt, which improves its pharmaceutical usability.
Supplied as the sulfate salt, which improves its pharmaceutical usability.
Mechanism of Action:
Selectively stimulates β2-adrenergic receptors in bronchial smooth muscle.
Activates adenylate cyclase, increases cAMP, leading to smooth muscle relaxation.
Causes rapid bronchodilation and relief from acute asthma attacks.
Pharmacokinetics:
Onset: Within 5–15 minutes (inhalation route).
Duration: 3–6 hours.
Metabolism: Hepatic (conjugation with sulfate).
Excretion: Mainly renal.
Selectively stimulates β2-adrenergic receptors in bronchial smooth muscle.
Activates adenylate cyclase, increases cAMP, leading to smooth muscle relaxation.
Causes rapid bronchodilation and relief from acute asthma attacks.
Pharmacokinetics:
Onset: Within 5–15 minutes (inhalation route).
Duration: 3–6 hours.
Metabolism: Hepatic (conjugation with sulfate).
Excretion: Mainly renal.
Primary Uses:
Relief and prevention of bronchospasm in asthma and COPD.
Management of exercise-induced bronchoconstriction.
Sometimes used off-label in hyperkalemia (shifts potassium into cells).
Dosage Forms:
Inhalers (MDI, DPI, nebulization).
Tablets and syrups.
Parenteral injection (in emergencies).
Relief and prevention of bronchospasm in asthma and COPD.
Management of exercise-induced bronchoconstriction.
Sometimes used off-label in hyperkalemia (shifts potassium into cells).
Dosage Forms:
Inhalers (MDI, DPI, nebulization).
Tablets and syrups.
Parenteral injection (in emergencies).
Fast-acting bronchodilator, essential in acute asthma management.
Considered safe and effective when used at recommended doses.
Side effects: Tremors, tachycardia, palpitations, hypokalemia, and nervousness.
Overuse may cause tolerance and reduced responsiveness.
Included on the WHO Model List of Essential Medicines.
Considered safe and effective when used at recommended doses.
Side effects: Tremors, tachycardia, palpitations, hypokalemia, and nervousness.
Overuse may cause tolerance and reduced responsiveness.
Included on the WHO Model List of Essential Medicines.
1kg/5kg/10kg/25kg Drum with LDPE bag/ TLA bag inside
Packed in HDPE drum
Stored in a clean,Cool,cry area keep away from
moisture and strong direct light/heat
Packed in HDPE drum
Stored in a clean,Cool,cry area keep away from
moisture and strong direct light/heat