Clenbuterol HCL
- Product Name: Clenbuterol HCL
- Product Code: AIL218CLE
- CAS No: 21898-19-1
- Grade: EP / USP
- Therapeutic Category: Bronchodilator / β2-adrenergic agonist (used in treatment of asthma, COPD; also known for off-label use in weight management and performance enhancement)
- Molecular Formula: C₁₂H₁₈Cl₂N₂O · HCl
- Molar Mass: 313.65 g/mol (hydrochloride salt)
- COA: Available
- MSDS: Available
- IUPAC Name: 1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanol hydrochloride
Clenbuterol HCl is a sympathomimetic amine and a selective β2-adrenergic receptor agonist. Though structurally similar to ephedrine and salbutamol, it is not approved for human use in some countries (like the US) but is used as a bronchodilator in others. It also gained notoriety in sports and bodybuilding for its fat-burning and anabolic-like effects.
It consists of a phenyl ring substituted with amino and dichloro groups, linked to an ethanol backbone with a tert-butylamino substituent, stabilized as a hydrochloride salt for improved solubility and bioavailability.
Mechanism of Action:
Stimulates β2-adrenergic receptors in smooth muscles.
Increases cyclic AMP (cAMP) via adenylate cyclase activation.
Leads to relaxation of bronchial muscles (bronchodilation).
Exhibits thermogenic properties by increasing metabolic activity and lipolysis.
Pharmacokinetics:
Oral bioavailability is high.
Long half-life (~36 hours), leading to sustained effects.
Metabolized hepatically and excreted renally.
Stimulates β2-adrenergic receptors in smooth muscles.
Increases cyclic AMP (cAMP) via adenylate cyclase activation.
Leads to relaxation of bronchial muscles (bronchodilation).
Exhibits thermogenic properties by increasing metabolic activity and lipolysis.
Pharmacokinetics:
Oral bioavailability is high.
Long half-life (~36 hours), leading to sustained effects.
Metabolized hepatically and excreted renally.
Approved Uses (in some countries):
Treatment of asthma and COPD (as a bronchodilator).
Veterinary medicine for respiratory issues in horses.
Off-label / Unapproved Uses:
Used (illegally in sports) as a performance-enhancing drug due to fat-burning and mild anabolic effects.
Sometimes misused for rapid weight loss.
Treatment of asthma and COPD (as a bronchodilator).
Veterinary medicine for respiratory issues in horses.
Off-label / Unapproved Uses:
Used (illegally in sports) as a performance-enhancing drug due to fat-burning and mild anabolic effects.
Sometimes misused for rapid weight loss.
Powerful β2-agonist with bronchodilator and metabolic stimulation effects.
Known for adverse effects like tachycardia, tremors, hypokalemia, and potential cardiac hypertrophy.
Must be handled with caution, with strict adherence to pharmaceutical guidelines.
Known for adverse effects like tachycardia, tremors, hypokalemia, and potential cardiac hypertrophy.
Must be handled with caution, with strict adherence to pharmaceutical guidelines.
1kg/5kg/10kg/25kg Drum with LDPE bag/ TLA bag inside
Packed in HDPE drum
Stored in a clean,Cool,cry area keep away from
moisture and strong direct light/heat
Packed in HDPE drum
Stored in a clean,Cool,cry area keep away from
moisture and strong direct light/heat