Etomidate
- Product Name: Etomidate
- Product Code: AIL331ETO
- CAS No: 33125-97-2
- Grade: BP / USP
- Therapeutic Category: General Anesthetic
- Molecular Formula: C14H16N2O2
- Molar Mass: ~244.29 g/mol
- COA: Available
- MSDS: Available
- IUPAC Name: R-1-(1-Phenylethyl)-1H-imidazole-5-carboxylate (commonly formulated as Etomidate propylene glycol solution for injection)
Name: Etomidate
CAS Number: 33125-97-2
IUPAC Name: R-1-(1-Phenylethyl)-1H-imidazole-5-carboxylate (commonly formulated as Etomidate propylene glycol solution for injection)
Molecular Formula: C14H16N2O2
Molar Mass: ~244.29 g/mol
CAS Number: 33125-97-2
IUPAC Name: R-1-(1-Phenylethyl)-1H-imidazole-5-carboxylate (commonly formulated as Etomidate propylene glycol solution for injection)
Molecular Formula: C14H16N2O2
Molar Mass: ~244.29 g/mol
Chemical Class: Imidazole derivative
Structure Description:
Structure Description:
- Contains an imidazole ring
- Substituted with an ester group
- Attached to a phenyl group via an ethyl chain
Category: General anesthetic (intravenous)
Mechanism of Action: Acts as a positive allosteric modulator of GABA-A receptors, enhancing inhibitory neurotransmission Produces hypnosis and anesthesia with minimal cardiovascular effects
Onset of Action: Rapid (within ~30–60 seconds of IV injection)
Duration: Short-acting (about 5–10 minutes after a single bolus dose)
Metabolism: Hepatic ester hydrolysis to inactive metabolites
Excretion: Mainly via urine
Mechanism of Action: Acts as a positive allosteric modulator of GABA-A receptors, enhancing inhibitory neurotransmission Produces hypnosis and anesthesia with minimal cardiovascular effects
Onset of Action: Rapid (within ~30–60 seconds of IV injection)
Duration: Short-acting (about 5–10 minutes after a single bolus dose)
Metabolism: Hepatic ester hydrolysis to inactive metabolites
Excretion: Mainly via urine
Induction of general anesthesia
Useful in patients with hemodynamic instability (minimal effect on heart rate and blood pressure)
Sometimes used for short procedures and rapid-sequence intubation
Useful in patients with hemodynamic instability (minimal effect on heart rate and blood pressure)
Sometimes used for short procedures and rapid-sequence intubation
Advantage: Stable cardiovascular profile compared to other IV anesthetics like propofol.
Limitation: Adrenal suppression (inhibits 11β-hydroxylase enzyme), so prolonged infusion is avoided.
Limitation: Adrenal suppression (inhibits 11β-hydroxylase enzyme), so prolonged infusion is avoided.
1kg/5kg/10kg/25kg Drum with LDPE bag/ TLA bag inside
Packed in HDPE drum
Stored in a clean,Cool,cry area keep away from
moisture and strong direct light/heat
Packed in HDPE drum
Stored in a clean,Cool,cry area keep away from
moisture and strong direct light/heat